Glutaraldehyde is a toxic chemical that is used as a cold sterilant to disinfect and clean heatsensitive medical, surgical and dental equipment. Cidex opa solution is the first new hld available in the last thirty years with the broad materials compatibility of glutaraldehyde. Its vapors have been associated with cases of occupational asthma, and the fda requires the all glutaraldehyde labels warn that the product should not be used outside a closed container. Apr 15, 2015 register now and get a free online msds binder.
Spills, deactivation, and disposal of glutaraldehyde. Glutaraldehyde solution grade i, 8% in h 2 o, specially purified for use as an electron microscopy fixative or other sophisticated use synonym. Evaluation of the efficacy of a 32% glutaraldehyde product for. The shelf life of the specific glutaraldehyde product can be found in section 7 of safety data sheet. Concentration of and exposure time to disinfectantsterilant. Pentanedial certifiedbioreagent recommended use laboratory chemicals. Cidex 14 day solution is a superior high level disinfectant using alkaline glutaraldehyde as the active agent. Can be reused for 28 days according to the required conditions for use. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database.
Cidex opa solution will provide rapid high level disinfection in 12 minutes at room temperature 20oc and is particularly active against mycobacteria, including glutaraldehyde resistant strains of m. Cidex is sold only in some of the european markets. Mar 09, 2019 cidex glutaraldehyde pdf % activated glutaraldehyde solution 5 liter bottle. Microbideg and cidex plustm 28, were directly compared, and two orthophthalaldehyde based products. The solution can also achieve some sporicidal activity with longer exposure time. Chemical and physical properties of glutaraldehyde. Ministry of labor regulation respecting the quality of the work environment components type value glutaraldehyde 118 ceiling 0. In a standard bod test4, more than 50% of glutaraldehyde is degraded in less than five days.
Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Exposure to glutaraldehyde may cause the following symptoms. Glutaraldehyde exhibits a chemical oxygen demand cod of 1. Cidex disinfectant comes in two options to meet individual sterilization needs. Cidex activated glutaraldehyde solution provides a wide spectrum efficacy against bacteria, mycobacteria, viruses and fungi. Effective against glutaraldehyderesistant mycrobacteria. Pdf effects of glutaraldehyde exposure on human health. In particular, this document evaluates and summarizes the literature describing the substances hazard potential and its assessment according to the scientific rationale and framework outlined in cib 61. Freezing will normally have no impact on the activity of glutaraldehyde based solutions. Regulatory information us federal regulations this product is hazardous according to osha 29 cfr 1910. Cidex opa solution is a quick and effective highlevel disinfectant used on a wide variety of semicritical, heatsensitive medical devices in medical facilities all over the world. Glutaraldehyde storage stability guidance safe use and.
These tungsten eye cisex are not recommended for use above 9 mev. The efficacy of cidex plus 32% alkaline glutaraldehyde was evaluated for the disinfection of fibreoptic endoscopes. P as f il 7714001 go to to download print test book log sheets. Cover the cidex solution sterilizing disinfecting tray with a secure lid. Glutaric dialdehyde solution, pentane 1, 5dial cas number 118. Sep 11, 2019 the file contains 1 pages and is free to view, download or print. Nitrile rubber and butyl rubber are suitable for use with up to 50% glutaraldehyde. A fast and effective way to disinfect a wide range of instruments and endoscopes. Cidex opa solution offers excellent materials compatibility and can therefore be used to disinfect a wide please refer to ifu and msds for complete details. Check solution each day of use or more frequently using the appropriate indicator. Glutaraldehyde highlevel semi critical device disinfectant. Glutaraldehyde water sterile for irrigation preservative free document. Material safety data sheet cidex plus 28 day solution tm trademark msds. Achieves high level disinfection in 20 minutes at 20 degree c, sporicidal activity of 10 hours at 25.
Cidex opa solution cidex opa solution was introduced by asp in 1999 to meet the need for effective, fast, easytouse highlevel disinfection and to address staff concerns about the safety of glutaraldehyde. Cidex opa solution test strips johns hopkins medicine. Provides rapid, costeffective, high level disinfection for a wide range of endoscopes and other medical instruments offers excellent tuberculocidal activity combined with the noncorrosive advantages of glutaraldehyde. Cidex opa is very effective against a wide range of microorganisms has a near neutral ph level. Cidex activated dialdehyde 14 day 1 gal, personal care. Cidex plus is a highlevel microbicidal disinfectant destroying harmful microorganisms within 20 minutes at 25 degrees celsius. Cidex opa cycle dilution was monitored by manufacturers test strips and highpressure liquid chromatography hplc. Kari, national toxicology program technical report on toxicity studies of glutaraldehyde administered by inhalation to f344n rats and b6c3f1 mice, nih publication 933348, 1993. Pdf inuse evaluation of perasafe r compared with cidex r in. Soak instruments for 12 minutes at 20c to achieve highlevel disinfection.
Employees at our production and blending facilities around the world. It has a wide spectrum of medical, scientific and industrial applications. Cidex activated dialdehyde solution test strips at. Exposure to glutaraldehyde can cause severe irritation to the skin, mucous membranes, and respiratory system. Cidex glutaraldehyde pdf % activated glutaraldehyde solution 5 liter bottle. As a medication, it is used to treat warts on the bottom of the feet. As a disinfectant, it is used to sterilize surgical instruments and other areas of hospitals. Glutaraldehyde highlevel semi critical device disinfectant liquid chemical sterilant and highlevel disinfectant for sterilizing and disinfecting reusable medical devices. Jan, 2019 cidex glutaraldehyde pdf % activated glutaraldehyde solution 5 liter bottle. Contraindications cidex opa concentrate and the in use solution should not be used to sterilize medical devices. This skin notation profile provides the sk assignment and supportive data for glutaraldehyde cas no.
Because heat and moisture are damaging to certain instruments, such as endoscopes, arthroscopes, and laparoscopes, cold disinfection with glutaraldehyde, a saturated dialdehyde cidex, omnicide 28, abcocide, can be used for these items. Cidex provides a rapid, costeffective high level disinfection for a wide range of endoscopes and other medical instruments. Occupational exposure limit values components type value glutaraldehyde 118 ceiling 0. Ensure all instruments are completely submersed in cidex opa solution, and if applicable, fill all lumens. It has a role as a crosslinking reagent, a disinfectant and a fixative. Cidex 14day alkaline glutaraldehyde for non corrosive. Glutaraldehydes properties as a chemical sterilant were initially recognized in the. Scott weese, in canine and feline infectious diseases, 2014. Pdf glutaraldehyde ga is widely used in the industrial, scientific and. Cidex activated glutaraldehyde solution offers excellent materials compatibility and can therefore be used to disinfect a wide range of medical instruments.
Nov 30, 2016 exposure to glutaraldehyde can cause severe irritation to the skin, mucous membranes, and respiratory system. Cidex activated dialdehyde solution co 245031 page 5 of 7 specific effects corrosive effects. While polyethylene and latex gloves are suitable for use with low concentrations of glutaraldehyde i. Do not use glutaraldehyde for surface disinfection osha. Jun 06, 2014 this skin notation profile provides the sk assignment and supportive data for glutaraldehyde cas no. Formaldehyde excels in such embalming scenarios as edema and produces rabid results that embalmers as a whole generally considers valuable. Chemical properties of glutaraldehyde cas 118 download as pdf file download as excel file download as 2d mole file predict properties. Uses advised against food, drug, pesticide or biocidal product use. Disinfection and sterilization in healthcare facilities wa rutala, dj weber, and hicpac, in press zoverview last centers for disease control and prevention guideline in 1985 274 pages pages preamble, 21 pages recommendations, glossary of terms, tablesfigures, 1100 references. As clinical experience is limited, an evaluation was undertaken in a busy endoscopy unit. Cidex opa solution will provide rapid high level disinfection in 12 minutes at room temperature 20oc and is particularly active against mycobacteria, including glutaraldehyderesistant strains of m. Cho, is a transparent oily, liquid with a pungent odor.
Cidex sale buy glutaraldehyde solution, cidex opa, cidex. Cidex opa solution will provide rapid high level disinfection in 5 minutes at a minimum of 250 cin a legally marketedautomatic endoscope reprocessor or 12 minutes at room temperature 200 c for manual processing. Since its introduction in 1999, cidex opa solution has become the world leading solution for highlevel disinfection used by thousands of healthcare facilities. Freezing will normally have no impact on the activity of glutaraldehydebased solutions. Cidex activated dialdehyde solution test strips from are semiquantitative chemical indicators for use in determining whether the concentration of glutaraldehyde, the active ingredient in cidex activated dialdehyde solution, is above or below the minimum effective concentration mec established for cidex activated dialdehyde solution. It is found in products such as cidex, aldesen, hospex, sporicidin, omnicide, matricide, wavicide and others. Antimicrobial efficacy of chemical disinfectants on. However, storage at elevated temperatures for extended periods will shorten the shelf life. Cidex glutaraldehyde pdf amaryl lids to download pdf you. Cidex opa, the highlevel disinfection standard usa medical.
For example, it is used in oil and gas recovery operations and pipelines, waste water treatment, xray processing, embalming fluid, leather tanning. Cidex opa, the highlevel disinfection standard usa. Its vapors have been associated with cases of occupational asthma, and the fda requires the all glutaraldehyde labels warn that the product should not be. New disinfectants for inactivation and disinfection of. Glutaraldehyde has broadspectrum antimicrobial activity and is the most widely used chemical for the highlevel disinfection of endoscopes and other such. Cidex glutaraldehyde pdf amaryl lids to download pdf. The file contains 1 pages and is free to view, download or print. Any of the grade i aqueous glutaraldehyde solutions can be used, but they need to be diluted with buffer down to a 1. Identification product name glutaric dialdehyde, 50 wt. Provide overview of disinfection and sterilization recommendations. Glutaraldehyde, sold under the brandname cidex and glutaral among others, is a disinfectant, medication, preservative, and fixative. Glutaraldehyde is a dialdehyde comprised of pentane with aldehyde functions at c1 and c5. Glutaraldehyde solution grade i, 8% in h2o, specially.
Cidex opa solution is bactericidal, sporicidal, virucidal, fungicidal, and tuberculocidal. Cidex is a fast and effective way to disinfect and sterilize a wide variety of medical devices and instruments. Glutaraldehyde is a colorless, oily liquid with a sharp, pungent odor. Safety data sheet creation date 19apr2010 revision date 03may2019 revision number 8 1. Glutaraldehyde is used for industrial, laboratory, agricultural, medical, and some household purposes, primarily for disinfecting and sterilization of surfaces and equipment. Some glutaraldehyde products have demonstrated a longer shelf life. Glutaraldehyde highlevel semicritical device disinfectant. Cidex opa solution is the first new hld available in the past thirty five years with the broad materials compatibility of glutaraldehyde.
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